Vol. 7, Issue 2, Part A (2025)

Background: Kapha Chintamani Rasa is a Khalveeya Rasaoushadi (herbo-mineral formulation) mentioned in the classical text of Rasendra Sara Sangraha.

Objective: To carry out the pharmaceutical study of Kapha Chintamani Rasa and to evaluate the physicochemical properties of Kapha Chintamani Rasa.

Methods: Kapha Chintamani Rasa contains ingredients such as Hingula (Cinnabar), Tankan (Borax), Rasa Sindoor (sulphide of Mercury), Marich (Piper nigrum), Indrayava seed (Holarrhena antidysenterica), Bhang Seed (Cannabis sativa), and Bhavana of Adhraka Swaras. All the above ingredients were blended uniformly to obtain a homogeneous mixture, from which Vatis were prepared.

Results: Analytical results of Kapha Chintamani Rasa were as follows: friability-0.05%, disintegration-26 min, pH-8.21, loss on drying-8.93%, total ash-13.95%, acid insoluble ash-2.34%, XRD-confirmed the presence of Cinnabar, mercury sulfide, Sodium borate.

Conclusion: Kapha Chintamani Rasa was prepared according to the classical reference of Rasendra Sara Sangraha. To date, no research work has been conducted on Kapha Chintamani Rasa; therefore, the present study aimed to evaluate the pharmaceutical and analytical profile of this formulation.