Dr. Maria Isabel Fernandez, Dr. Pedro Luiz Carvalho and Dr. Catalina Gomez Velasco
This study evaluated the role of Ficus carica (common fig) in the prevention and management of diabetes mellitus through its bioactive compounds, including phenolic acids and flavonoids, which exhibit antioxidant and antihyperglycemic properties. Bioactive extracts were prepared using aqueous and ethanolic solvents and tested for their antioxidant capacity and inhibitory effects on carbohydrate-metabolizing enzymes. Animal models treated with Ficus carica extracts demonstrated significant improvements in fasting blood glucose levels, insulin sensitivity, and lipid profiles. Human clinical trials revealed a reduction in HbA1c and fasting blood glucose levels following fig fruit supplementation. The study concluded that Ficus carica offers potential as a complementary therapy for diabetes management, with further clinical trials recommended to validate its efficacy and safety.
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